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Involvement of Mutation in ampD I, mrcA, and at Least One Additional Gene in β-Lactamase Hyperproduction in Stenotrophomonas maltophilia

It has been reported that targeted disruption of ampD I or mrcA causes β-lactamase hyperproduction in Stenotrophomonas maltophilia. We show here that β-lactamase-hyperproducing laboratory selected mutants and clinical isolates can have wild-type ampD I and mrcA genes, implicating mutation of at leas...

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Main Authors: Talfan, Asmaa, Mounsey, Oliver, Charman, Matthew, Townsend, Eleanor, Avison, Matthew B.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811264/
https://ncbi.nlm.nih.gov/pubmed/23979761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01446-13
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