Risk Factors for Treatment Failure of Polymyxin B Monotherapy for Carbapenem-Resistant Klebsiella pneumoniae Infections

Polymyxins are reserved for salvage therapy of infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). Though synergy has been demonstrated for the combination of polymyxins with carbapenems or tigecycline, in vitro synergy tests are nonstandardized, and the clinical effect of synerg...

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Detalhes bibliográficos
Main Authors: Dubrovskaya, Yanina, Chen, Ting-Yi, Scipione, Marco R., Esaian, Diana, Phillips, Michael S., Papadopoulos, John, Mehta, Sapna A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3811259/
https://ncbi.nlm.nih.gov/pubmed/23959321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00510-13
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