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HIV-1 Nef and T-cell activation: a history of contradictions

HIV-1 Nef is a multifunctional viral protein that contributes to higher plasma viremia and more rapid disease progression. Nef appears to accomplish this, in part, through modulation of T-cell activation; however, the results of these studies over the past 25 years have been inconsistent. Here, the...

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Autores principales: Markle, Tristan J, Philip, Mwimanzi, Brockman, Mark A
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810967/
https://ncbi.nlm.nih.gov/pubmed/24187576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.13.20
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