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Diffusion-limited contact formation in unfolded cytochrome c: estimating the maximum rate of protein folding.

How fast can a protein fold? The rate of polypeptide collapse to a compact state sets an upper limit to the rate of folding. Collapse may in turn be limited by the rate of intrachain diffusion. To address this question, we have determined the rate at which two regions of an unfolded protein are brou...

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Detalhes bibliográficos
Main Authors: Hagen, S J, Hofrichter, J, Szabo, A, Eaton, W A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC38106/
https://ncbi.nlm.nih.gov/pubmed/8876184
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