Diffusion-limited contact formation in unfolded cytochrome c: estimating the maximum rate of protein folding.
How fast can a protein fold? The rate of polypeptide collapse to a compact state sets an upper limit to the rate of folding. Collapse may in turn be limited by the rate of intrachain diffusion. To address this question, we have determined the rate at which two regions of an unfolded protein are brou...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38106/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11615 |
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