Contribution of higher risk genes and European admixture to Crohn's disease in African Americans

BACKGROUND & AIMS: African Americans (AA) are an admixed population of West African (WA) and European ancestry (EA). Crohn's disease (CD) susceptibility genes have not been established. We therefore evaluated the contribution of European admixture and major established risk genes to AA CD....

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Main Authors: Wang, Ming-Hsi, Okazaki, Toshihiko, Kugathasan, Subra, Cho, Judy H., Isaacs, Kim L., Lewis, James D., Smoot, Duane T., Valentine, John F., Kader, Howard A., Ford, Jean G., Harris, Mary L., Oliva-Hemker, Maria, Cuffari, Carmen, Torbenson, Michael S., Duerr, Richard H., Silverberg, Mark S., Rioux, John D., Taylor, Kent D., Nguyen, Geoffrey C., Wu, Yuqiong, Datta, Lisa W., Hooker, Stanley, Dassopoulos, Themistocles, Kittles, Rick A., Kao, Linda W.H., Brant, Steven R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810419/
https://ncbi.nlm.nih.gov/pubmed/22411504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.22931
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