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The common NOD2 risk variants in African Americans with Crohn’s disease are due exclusively to recent Caucasian admixture

BACKGROUND: Crohn’s disease (CD) is highly heritable. NOD2 has emerged as the main susceptibility gene among individuals of European ancestry; however, NOD2 does not appear to contribute to CD susceptibility among many non-European populations. Today’s African American (AA) population represents an...

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Detalhes bibliográficos
Main Authors: Adeyanju, Oloruntosin, Okou, David, Huang, Clifton, Kumar, Archana, Sauer, Cary, Galloway, Courtney, Prasad, Mahadev, Waters, Jon, Cutler, David, Zwick, Michael, Dhere, Tanvi, Kugathasan, Subra
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3392535/
https://ncbi.nlm.nih.gov/pubmed/22447396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.22944
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