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The contrasting roles of lamin B1 in cellular aging and human disease
The nuclear lamina underlies the inner nuclear membrane and consists of a proteinaceous meshwork of intermediate filaments: the A- and B-type lamins. Mutations in LMNA (encoding lamin A and C) give rise to a variety of human diseases including muscular dystrophies, cardiomyopathies and the premature...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2013
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3810336/ https://ncbi.nlm.nih.gov/pubmed/23873483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.25808 |
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