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Monitoring antifolate resistance in intermittent preventive therapy for malaria

Mutations in the Plasmodium falciparum genes Pfdhfr and Pfdhps have rendered sulfadoxine-pyrimethamine (SP) ineffective for malaria treatment in most regions of the world. Yet, SP is efficacious as intermittent preventive therapy in pregnant women (IPTp) and infants (IPTi) and as seasonal malaria co...

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Detalhes bibliográficos
Main Authors: Venkatesan, Meera, Alifrangis, Michael, Roper, Cally, Plowe, Christopher V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810209/
https://ncbi.nlm.nih.gov/pubmed/23948432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pt.2013.07.008
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