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CpG or IFN-α are more potent adjuvants than GM-CSF to promote anti-tumor immunity following idiotype vaccine in multiple myeloma

Idiotype (Id) protein in combination with GM-CSF has been used as vaccines for immunotherapy of patients with myeloma and B-cell tumors and the results have been disappointing. To search for better immune adjuvants to improve the efficacy of Id-based immunotherapy in myeloma, we evaluated and compar...

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Detalhes bibliográficos
Main Authors: Hong, Sungyoul, Qian, Jianfei, Li, Haiyan, Yang, Jing, Lu, Yong, Zheng, Yuhuan, Yi, Qing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810206/
https://ncbi.nlm.nih.gov/pubmed/22002243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-011-1123-2
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