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Variation in Cell Signaling Protein Expression May Introduce Sampling Bias in Primary Epithelial Ovarian Cancer

Although the expression of cell signaling proteins is used as prognostic and predictive biomarker, variability of protein levels within tumors is not well studied. We assessed intratumoral heterogeneity of protein expression within primary ovarian cancer. Full-length proteins were extracted from 88...

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Detalhes bibliográficos
Main Authors: Mittermeyer, Gabriele, Malinowsky, Katharina, Beese, Christian, Höfler, Heinz, Schmalfeldt, Barbara, Becker, Karl-Friedrich, Avril, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810127/
https://ncbi.nlm.nih.gov/pubmed/24204986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077825
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