Common Protein Biomarkers Assessed by Reverse Phase Protein Arrays Show Considerable Intratumoral Heterogeneity in Breast Cancer Tissues

Proteins are used as prognostic and predictive biomarkers in breast cancer. However, the variability of protein expression within the same tumor is not well studied. The aim of this study was to assess intratumoral heterogeneity in protein expression levels by reverse-phase-protein-arrays (RPPA) (i)...

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Bibliographic Details
Main Authors: Malinowsky, Katharina, Raychaudhuri, Mithu, Buchner, Theresa, Thulke, Sabrina, Wolff, Claudia, Höfler, Heinz, Becker, Karl-Friedrich, Avril, Stefanie
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3390380/
https://ncbi.nlm.nih.gov/pubmed/22792263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040285
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