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Enhanced antibody responses to a detoxified lipopolysaccharide-group B meningococcal outer membrane protein vaccine are due to synergistic engagement of TLR

When given passively or elicited actively, antibodies induced by a detoxified E. coli Rc chemotype (J5) mutant lipopolysaccharide (J5dLPS) -group B meningococcal outer membrane protein (OMP) complex vaccine protected animals from lethal sepsis. The protection from sepsis is believed to be dependent...

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Detalhes bibliográficos
Main Authors: Chen, Wilbur H., Basu, Subhendu, Bhattacharjee, Apurba K., Cross, Alan S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810117/
https://ncbi.nlm.nih.gov/pubmed/19822632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425909346973
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