Proteinuria Impairs Podocyte Regeneration by Sequestering Retinoic Acid

In CKD, the risk of kidney failure and death depends on the severity of proteinuria, which correlates with the extent of podocyte loss and glomerular scarring. We investigated whether proteinuria contributes directly to progressive glomerulosclerosis through the suppression of podocyte regeneration...

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Main Authors: Peired, Anna, Angelotti, Maria Lucia, Ronconi, Elisa, la Marca, Giancarlo, Mazzinghi, Benedetta, Sisti, Alessandro, Lombardi, Duccio, Giocaliere, Elisa, Della Bona, Marialuisa, Villanelli, Fabio, Parente, Eliana, Ballerini, Lara, Sagrinati, Costanza, Wanner, Nicola, Huber, Tobias B., Liapis, Helen, Lazzeri, Elena, Lasagni, Laura, Romagnani, Paola
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2013
Assuntos:
Basic Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810076/
https://ncbi.nlm.nih.gov/pubmed/23949798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012090950
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