Proteinuria Impairs Podocyte Regeneration by Sequestering Retinoic Acid

In CKD, the risk of kidney failure and death depends on the severity of proteinuria, which correlates with the extent of podocyte loss and glomerular scarring. We investigated whether proteinuria contributes directly to progressive glomerulosclerosis through the suppression of podocyte regeneration...

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Главные авторы: Peired, Anna, Angelotti, Maria Lucia, Ronconi, Elisa, la Marca, Giancarlo, Mazzinghi, Benedetta, Sisti, Alessandro, Lombardi, Duccio, Giocaliere, Elisa, Della Bona, Marialuisa, Villanelli, Fabio, Parente, Eliana, Ballerini, Lara, Sagrinati, Costanza, Wanner, Nicola, Huber, Tobias B., Liapis, Helen, Lazzeri, Elena, Lasagni, Laura, Romagnani, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Nephrology 2013
Предметы:
Basic Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810076/
https://ncbi.nlm.nih.gov/pubmed/23949798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012090950
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