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Pepsinized cashew proteins are hypoallergenic and immunogenic and provide effective immunotherapy in mice with cashew allergy

BACKGROUND: IgE-mediated allergic reactions to cashews and other nuts can trigger life-threatening anaphylaxis. Proactive therapies to decrease reaction severity do not exist. OBJECTIVES: We aimed to determine the efficacy of pepsin-digested cashew proteins used as immunotherapy in a murine model of...

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Autori principali: Kulis, Mike, MacQueen, Ian, Li, Yifan, Guo, Rishu, Zhong, Xiao-Ping, Burks, A. Wesley
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810066/
https://ncbi.nlm.nih.gov/pubmed/22795369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2012.05.044
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