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Maternal SNPs in the p53 Pathway: Risk Factors for Trisomy 21?

The p53 family and its regulatory pathway play an important role as regulators of developmental processes, limiting the propagation of aneuploid cells. Its dysfunction or imbalance can lead to pathological abnormalities in humans. The aim of this study was to evaluate the effect of maternal polymorp...

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Detalhes bibliográficos
Main Authors: Boquett, Juliano André, Brandalize, Ana Paula Carneiro, Fraga, Lucas Rosa, Schuler-Faccini, Lavínia
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809983/
https://ncbi.nlm.nih.gov/pubmed/23089923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2012-00937
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