Human breast cancer cells harboring a gatekeeper T798M mutation in HER2 overexpress EGFR ligands and are sensitive to dual inhibition of EGFR and HER2

Lignende værker

• H1047R phosphatidylinositol 3-kinase mutant enhances HER2-mediated transformation via heregulin production and activation of HER3
  af: Chakrabarty, Anindita, et al.
  Udgivet: (2010)
• An acquired HER2 T798I gatekeeper mutation induces resistance to neratinib in a patient with HER2 mutant-driven breast cancer
  af: Hanker, Ariella B., et al.
  Udgivet: (2017)
• Intrinsic and Acquired Resistance to HER2-Targeted Therapies in HER2 Gene-Amplified Breast Cancer: Mechanisms and Clinical Implications
  af: Rexer, Brent N., et al.
  Udgivet: (2012)
• Optical imaging of metabolism in HER2 overexpressing breast cancer cells
  af: Walsh, Alex, et al.
  Udgivet: (2011)
• Overcoming resistance to tyrosine kinase inhibitors: Lessons learned from cancer cells treated with EGFR antagonists
  af: Rexer, Brent N., et al.
  Udgivet: (2009)