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β(2) integrins inhibit TLR responses by regulating NF-κB pathway and p38 MAPK activation
Outside-in signals from β(2) integrins require immunoreceptor tyrosine-based activation motif (ITAM) adapters in myeloid cells, which are known to dampen TLR responses. However, the relationship between β(2) integrins and TLR regulation is unclear. Here we show that deficiency in β(2) integrins (Itg...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809911/ https://ncbi.nlm.nih.gov/pubmed/23310953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201242550 |
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