Tussilagone Inhibits Osteoclastogenesis and Periprosthetic Osteolysis by Suppressing the NF-κB and P38 MAPK Signaling Pathways

BackgroundAseptic prosthetic loosening is one of the main factors causing poor prognosis of limb function after joint replacement and requires troublesome revisional surgery. It is featured by wear particle-induced periprosthetic osteolysis mediated by excessive osteoclasts activated in inflammatory...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Main Authors: Xuantao Hu, Ziqing Yin, Xia Chen, Guangyao Jiang, Daishui Yang, Ziqin Cao, Shuai Li, Zicheng Liu, Dan Peng, Pengcheng Dou
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2020-04-01
Sraith:Frontiers in Pharmacology
Ábhair:
tussilagone
osteoclast
NF-κB
p38
MAPK
aseptic prosthetic loosening
Rochtain Ar Líne:https://www.frontiersin.org/article/10.3389/fphar.2020.00385/full
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla