Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant

Lumbar disc degeneration (LDD) is associated with both genetic and environmental factors and affects many people worldwide. A hallmark of LDD is loss of proteoglycan and water content in the nucleus pulposus of intervertebral discs. While some genetic determinants have been reported, the etiology of...

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Detalhes bibliográficos
Main Authors: Song, You-Qiang, Karasugi, Tatsuki, Cheung, Kenneth M.C., Chiba, Kazuhiro, Ho, Daniel W.H., Miyake, Atsushi, Kao, Patrick Y.P., Sze, Kit Ling, Yee, Anita, Takahashi, Atsushi, Kawaguchi, Yoshiharu, Mikami, Yasuo, Matsumoto, Morio, Togawa, Daisuke, Kanayama, Masahiro, Shi, Dongquan, Dai, Jin, Jiang, Qing, Wu, Chengai, Tian, Wei, Wang, Na, Leong, John C.Y., Luk, Keith D.K., Yip, Shea-ping, Cherny, Stacey S., Wang, Junwen, Mundlos, Stefan, Kelempisioti, Anthi, Eskola, Pasi J., Männikkö, Minna, Mäkelä, Pirkka, Karppinen, Jaro, Järvelin, Marjo-Riitta, O’Reilly, Paul F., Kubo, Michiaki, Kimura, Tomoatsu, Kubo, Toshikazu, Toyama, Yoshiaki, Mizuta, Hiroshi, Cheah, Kathryn S.E., Tsunoda, Tatsuhiko, Sham, Pak-Chung, Ikegawa, Shiro, Chan, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809787/
https://ncbi.nlm.nih.gov/pubmed/24216480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69277
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