Lumbar disc degeneration is linked to a carbohydrate sulfotransferase 3 variant

Lumbar disc degeneration (LDD) is associated with both genetic and environmental factors and affects many people worldwide. A hallmark of LDD is loss of proteoglycan and water content in the nucleus pulposus of intervertebral discs. While some genetic determinants have been reported, the etiology of...

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Auteurs principaux: Song, You-Qiang, Karasugi, Tatsuki, Cheung, Kenneth M.C., Chiba, Kazuhiro, Ho, Daniel W.H., Miyake, Atsushi, Kao, Patrick Y.P., Sze, Kit Ling, Yee, Anita, Takahashi, Atsushi, Kawaguchi, Yoshiharu, Mikami, Yasuo, Matsumoto, Morio, Togawa, Daisuke, Kanayama, Masahiro, Shi, Dongquan, Dai, Jin, Jiang, Qing, Wu, Chengai, Tian, Wei, Wang, Na, Leong, John C.Y., Luk, Keith D.K., Yip, Shea-ping, Cherny, Stacey S., Wang, Junwen, Mundlos, Stefan, Kelempisioti, Anthi, Eskola, Pasi J., Männikkö, Minna, Mäkelä, Pirkka, Karppinen, Jaro, Järvelin, Marjo-Riitta, O’Reilly, Paul F., Kubo, Michiaki, Kimura, Tomoatsu, Kubo, Toshikazu, Toyama, Yoshiaki, Mizuta, Hiroshi, Cheah, Kathryn S.E., Tsunoda, Tatsuhiko, Sham, Pak-Chung, Ikegawa, Shiro, Chan, Danny
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2013
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3809787/
https://ncbi.nlm.nih.gov/pubmed/24216480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69277
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