A Functional Polymorphism in THBS2 that Affects Alternative Splicing and MMP Binding Is Associated with Lumbar-Disc Herniation

Lumbar-disc herniation (LDH), one of the most common musculoskeletal diseases, has strong genetic determinants. Recently, several genes that encode extracellular matrix (ECM) proteins in the intervertebral disc have been reported to associate with LDH. Thrombospondins (THBSs) 1 and 2 are good candid...

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محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hirose, Yuichiro, Chiba, Kazuhiro, Karasugi, Tatsuki, Nakajima, Masahiro, Kawaguchi, Yoshiharu, Mikami, Yasuo, Furuichi, Tatsuya, Mio, Futoshi, Miyake, Atsushi, Miyamoto, Takeshi, Ozaki, Kouichi, Takahashi, Atsushi, Mizuta, Hiroshi, Kubo, Toshikazu, Kimura, Tomoatsu, Tanaka, Toshihiro, Toyama, Yoshiaki, Ikegawa, Shiro
التنسيق: Artigo
اللغة:Inglês
منشور في: American Society of Human Genetics 2008
الموضوعات:
Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2427305/
https://ncbi.nlm.nih.gov/pubmed/18455130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.03.013
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