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Ligand Binding Analysis and Screening by Chemical Denaturation Shift
The identification of small molecule ligands is an important first step in drug development, especially drugs that target proteins with no intrinsic activity. Towards this goal, it is important to have access to technologies that are able to measure binding affinities for a large number of potential...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3809086/ https://ncbi.nlm.nih.gov/pubmed/23994566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2013.08.015 |
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