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Targeting Presynaptic Norepinephrine Transporter in Brown Adipose Tissue: A Novel Imaging Approach and Potential Treatment for Diabetes and Obesity

Brown adipose tissue (BAT) plays a significant role in metabolism. In this study, we report the use of atomoxetine (a clinically applicable norepinephrine reuptake inhibitor) for (18)F-FDG PET imaging of BAT and its effects on heat production and blood glucose concentration. Fasted-male Sprague-Dawl...

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Detalhes bibliográficos
Main Authors: MIRBOLOOKI, M. REZA, CONSTANTINESCU, CRISTIAN C., PAN, MIN-LIANG, MUKHERJEE, JOGESHWAR
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808851/
https://ncbi.nlm.nih.gov/pubmed/23080264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21617
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