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Enhancement of (18)F-Fluorodeoxyglucose Metabolism in Rat Brain Frontal Cortex Using a β3 Adrenoceptor Agonist

We report the use of β3-adrenergic receptor mediated activation of rat brain frontal cortex using mirabegron (a selective β3-adrenoceptor agonist), measured by (18)F-FDG PET/CT. Another β3-agonis t, CL 316,243, did not have this effect due to impermeability through the blood brain barrier (BBB), whi...

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Bibliografske podrobnosti
izdano v:Synapse
Main Authors: Mirbolooki, M. Reza, Schade, Kimberly N., Constantinescu, Cristian C., Pan, Min-Liang, Mukherjee, Jogeshwar
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275345/
https://ncbi.nlm.nih.gov/pubmed/25347981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21789
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