Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

T-cells have to recognize peptides presented on MHC molecules to be activated and elicit their effector functions. Several studies demonstrate that some peptides are more immunogenic than others and therefore more likely to be T-cell epitopes. We set out to determine which properties cause such diff...

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Bibliografski detalji
Glavni autori: Calis, Jorg J. A., Maybeno, Matt, Greenbaum, Jason A., Weiskopf, Daniela, De Silva, Aruna D., Sette, Alessandro, Keşmir, Can, Peters, Bjoern
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808449/
https://ncbi.nlm.nih.gov/pubmed/24204222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003266
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