A Phase I Trial of Isolated Hepatic Perfusion (IHP) Using 5-FU and Oxaliplatin in Patients with Unresectable Isolated Liver Metastases from Colorectal Cancer

BACKGROUND: Isolated hepatic perfusion (IHP) with melphalan is an established approach for patients with unresectable metastatic liver lesions. This study determined the safety and maximum tolerated dose (MTD) of 5-FU with oxaliplatin via IHP. METHODS: Standard 3 × 3 Phase I design. Subjects with un...

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Main Authors: Magge, D., Zureikat, A. H., Bartlett, D. L., Holtzman, M. P., Choudry, H. A., Beumer, J. H., Pingpank, J. F., Holleran, J. L., Strychor, S., Cunningham, D. E., Jones, H. L., Zeh, H. J.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808182/
https://ncbi.nlm.nih.gov/pubmed/23575907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-013-2960-3
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