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Quantitative Phosphoproteomics Identifies Substrates and Functional Modules of Aurora and Polo-Like Kinase Activities in Mitotic Cells

Mitosis is a process involving a complex series of events that require careful coordination. Protein phosphorylation by a small number of kinases, in particular Aurora A, Aurora B, the cyclin-dependent kinase–cyclin complex Cdk1/cyclinB, and Polo-like kinase 1 (Plk1), orchestrates almost every step...

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Main Authors: Kettenbach, Arminja N., Schweppe, Devin K., Faherty, Brendan K., Pechenick, Dov, Pletnev, Alexandre A., Gerber, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3808085/
https://ncbi.nlm.nih.gov/pubmed/21712546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2001497
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