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Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin
Bifunctional alkylating agent sulfur mustard (SM) and its analog nitrogen mustard (NM) cause DNA damage leading to cell death, and potentially activating inflammation. Transcription factor p53 plays a critical role in DNA damage by regulating cell cycle progression and apoptosis. Earlier studies by...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3808076/ https://ncbi.nlm.nih.gov/pubmed/23845566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.06.013 |
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