Ethyl cellulose and hydroxypropyl methyl cellulose buoyant microspheres of metoprolol succinate: Influence of pH modifiers

INTRODUCTION: Incorporation of pH modifier has been the usual strategy employed to enhance the dissolution of weakly basic drug from floating microspheres. Microspheres prepared using a combination of both ethyl cellulose (EC) and hydroxypropyl methylcellulose (HPMC) which shows highest release were...

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Bibliografiske detaljer
Main Authors: Raut, Neha S, Somvanshi, Sachin, Jumde, Amol B, Khandelwal, Harsha M, Umekar, Milind J, Kotagale, Nandkishor Ramdas
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications & Media Pvt Ltd 2013
Fag:
Original Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807984/
https://ncbi.nlm.nih.gov/pubmed/24167789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/2230-973X.119235
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