Transferrin-conjugated lipid-coated PLGA nanoparticles for targeted delivery of aromatase inhibitor 7α-APTADD to breast cancer cells

Transferrin (Tf)-conjugated lipid-coated poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles carrying the aromatase inhibitor, 7α-(4′-amino)phenylthio-1,4-androstadiene-3,17-dione (7α-APTADD), were synthesized by a solvent injection method. Formulation parameters including PLGA-to-lipid, egg PC-to-T...

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Huvudupphovsmän: Zheng, Yu, Yu, Bo, Weecharangsan, Wanlop, Piao, Longzhu, Darby, Michael, Mao, Yicheng, Koynova, Rumiana, Yang, Xiaojuan, Li, Hong, Xu, Songlin, Lee, L. James, Sugimoto, Yasuro, Brueggemeier, Robert W., Lee, Robert J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807850/
https://ncbi.nlm.nih.gov/pubmed/20156537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpharm.2010.02.008
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