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MacA, a Periplasmic Membrane Fusion Protein of the Macrolide Transporter MacAB-TolC, Binds Lipopolysaccharide Core Specifically and with High Affinity

The Escherichia coli MacAB-TolC transporter has been implicated in efflux of macrolide antibiotics and secretion of enterotoxin STII. In this study, we found that purified MacA, a periplasmic membrane fusion protein, contains one tightly bound rough core lipopolysaccharide (R-LPS) molecule per MacA...

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Detalhes bibliográficos
Main Authors: Lu, Shuo, Zgurskaya, Helen I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807484/
https://ncbi.nlm.nih.gov/pubmed/23974027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00756-13
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