Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump

The MacA-MacB-TolC assembly of Escherichia coli is a transmembrane machine that spans the cell envelope and actively extrudes substrates, including macrolide antibiotics and polypeptide virulence factors. These transport processes are energized by the ATPase MacB, a member of the ATP-binding cassett...

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Udgivet i:Nat Microbiol
Main Authors: Fitzpatrick, Anthony W.P., Llabrés, Salomé, Neuberger, Arthur, Blaza, James N., Bai, Xiao-chen, Okada, Ui, Murakami, Satoshi, van Veen, Hendrik W., Zachariae, Ulrich, Scheres, Sjors H.W., Luisi, Ben F., Du, Dijun
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5447821/
https://ncbi.nlm.nih.gov/pubmed/28504659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2017.70
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