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Structure-Function Analysis of MurJ Reveals a Solvent-Exposed Cavity Containing Residues Essential for Peptidoglycan Biogenesis in Escherichia coli

Gram-negative bacteria such as Escherichia coli build a peptidoglycan (PG) cell wall in their periplasm using the precursor known as lipid II. Lipid II is a large amphipathic molecule composed of undecaprenyl diphosphate and a disaccharide-pentapeptide that PG-synthesizing enzymes use to build the P...

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Detalhes bibliográficos
Main Authors: Butler, Emily K., Davis, Rebecca M., Bari, Vase, Nicholson, Paul A., Ruiz, Natividad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807429/
https://ncbi.nlm.nih.gov/pubmed/23935042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00731-13
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