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Pattern Recognition Receptor MDA5 Modulates CD8(+) T Cell-Dependent Clearance of West Nile Virus from the Central Nervous System
Many viruses induce type I interferon responses by activating cytoplasmic RNA sensors, including the RIG-I-like receptors (RLRs). Although two members of the RLR family, RIG-I and MDA5, have been implicated in host control of virus infection, the relative role of each RLR in restricting pathogenesis...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Microbiology
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807324/ https://ncbi.nlm.nih.gov/pubmed/23966390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01403-13 |
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