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Cytokine-Dependent Induction of CD4(+) T cells with Cytotoxic Potential during Influenza Virus Infection

Recent evidence has identified the role of granzyme B- and perforin-expressing CD4(+) T cells with cytotoxic potential in antiviral immunity. However, the in vivo cytokine cues and downstream pathways governing the differentiation of these cells are unclear. Here, we have identified that CD4(+) T ce...

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Detalhes bibliográficos
Main Authors: Hua, Laiqing, Yao, Shuyu, Pham, Duy, Jiang, Li, Wright, Jeffrey, Sawant, Deepali, Dent, Alexander L., Braciale, Thomas J., Kaplan, Mark H., Sun, Jie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807312/
https://ncbi.nlm.nih.gov/pubmed/23986597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01461-13
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