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Induction of CD4(+) T-Cell-Independent Immunoglobulin Responses by Inactivated Influenza Virus

Through cognate interaction between antigen-specific B-cell and CD4(+) αβ T cells, the CD4(+) αβ T cells secrete cytokines that initiate immunoglobulin (Ig) class switching from IgM to IgG. In this study, we show that formalin-inactivated influenza PR8 virus induces virus-specific IgM and IgG respon...

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Detalhes bibliográficos
Main Authors: Sha, Zhiyi, Compans, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC110851/
https://ncbi.nlm.nih.gov/pubmed/10799573
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