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Compensatory Mutants of the Bovine Papillomavirus E5 Protein and the Platelet-Derived Growth Factor β Receptor Reveal a Complex Direct Transmembrane Interaction

The 44-amino-acid E5 protein of bovine papillomavirus is a dimeric transmembrane protein that exists in a stable complex with the platelet-derived growth factor (PDGF) β receptor, causing receptor activation and cell transformation. The transmembrane domain of the PDGF β receptor is required for com...

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Bibliographic Details
Main Authors: Edwards, Anne P. B., Xie, Yanhua, Bowers, Lara, DiMaio, Daniel
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807273/
https://ncbi.nlm.nih.gov/pubmed/23926343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01475-13
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