Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome

The cyclic dinucleotides 3'-5'diadenylate (c-diAMP) and 3'-5' diguanylate (c-diGMP) are important bacterial second messengers that have recently been shown to stimulate the secretion of type I Interferons (IFN-Is) through the c-diGMP-binding protein MPYS/STING. Here, we show that...

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Detalhes bibliográficos
Main Authors: Abdul-Sater, Ali A, Tattoli, Ivan, Jin, Lei, Grajkowski, Andrzej, Levi, Assaf, Koller, Beverly H, Allen, Irving C, Beaucage, Serge L, Fitzgerald, Katherine A, Ting, Jenny P -Y, Cambier, John C, Girardin, Stephen E, Schindler, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807221/
https://ncbi.nlm.nih.gov/pubmed/24008845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2013.132
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