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An improved strategy for the chemical synthesis of 3’, 5’-cyclic diguanylic acid: Chemical synthesis of native c-di-GMP

The physiological functions of c-di-GMP and its involvement in many key processes led to its recognition as a major and ubiquitous bacterial second messenger. Aside from being a bacterial signaling molecule, c-di-GMP is also an immunostimulatory molecule capable of inducing innate and adaptive immun...

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Detalhes bibliográficos
Publicado no:Curr Protoc Nucleic Acid Chem
Main Authors: Grajkowski, Andrzej, Takahashi, Mayumi, Kaczyński, Tomasz, Srivastava, Suresh C., Beaucage, Serge L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6581608/
https://ncbi.nlm.nih.gov/pubmed/30970180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpnc.84
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