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Mutagenesis and Enrichment of Auxotrophs in Penicillium chrysogenum

An efficient method for isolation of auxotrophs of Penicillium chyrysogenum involving mutagenesis with ethyl methanesulfonate followed by enrichment with sodium pentachlorophenate was developed. The auxotroph frequencies obtained were 30 to 40%.

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Detalhes bibliográficos
Main Authors: Masurekar, Prakash S., Kahgan, Marc P., Demain, Arnold L.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC380710/
https://ncbi.nlm.nih.gov/pubmed/4346628
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