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Mutagenesis and Enrichment of Auxotrophs in Penicillium chrysogenum

An efficient method for isolation of auxotrophs of Penicillium chyrysogenum involving mutagenesis with ethyl methanesulfonate followed by enrichment with sodium pentachlorophenate was developed. The auxotroph frequencies obtained were 30 to 40%.

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Autors principals: Masurekar, Prakash S., Kahgan, Marc P., Demain, Arnold L.
Format: Artigo
Idioma:Inglês
Publicat: 1972
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC380710/
https://ncbi.nlm.nih.gov/pubmed/4346628
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