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High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells

The traditional method for studying cancer in vitro is to grow immortalized cancer cells in two-dimensional monolayers on plastic. However, many cellular features are impaired in these artificial conditions, and large changes in gene expression compared to tumors have been reported. Three-dimensiona...

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Detalhes bibliográficos
Main Authors: Hongisto, Vesa, Jernström, Sandra, Fey, Vidal, Mpindi, John-Patrick, Kleivi Sahlberg, Kristine, Kallioniemi, Olli, Perälä, Merja
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806867/
https://ncbi.nlm.nih.gov/pubmed/24194875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077232
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