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High-Throughput 3D Screening Reveals Differences in Drug Sensitivities between Culture Models of JIMT1 Breast Cancer Cells

The traditional method for studying cancer in vitro is to grow immortalized cancer cells in two-dimensional monolayers on plastic. However, many cellular features are impaired in these artificial conditions, and large changes in gene expression compared to tumors have been reported. Three-dimensiona...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Hongisto, Vesa, Jernström, Sandra, Fey, Vidal, Mpindi, John-Patrick, Kleivi Sahlberg, Kristine, Kallioniemi, Olli, Perälä, Merja
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806867/
https://ncbi.nlm.nih.gov/pubmed/24194875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077232
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