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Characterization of the Akt2 Domain Essential for Binding Nuclear p21cip1 to Promote Cell Cycle Arrest during Myogenic Differentiation

The binding of the cdk inhibitor p21cip1 to Akt2 in the nucleus is an essential component in determining the specific role of Akt2 in the cell cycle arrest that precedes myogenic differentiation. Here, through a combination of biochemical and cell biology approaches, we have addressed the molecular...

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書目詳細資料
Main Authors: Heron-Milhavet, Lisa, Franckhauser, Celine, Fernandez, Anne, Lamb, Ned J.
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806761/
https://ncbi.nlm.nih.gov/pubmed/24194853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076987
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