Rhein Protects Pancreatic β-Cells From Dynamin-Related Protein-1–Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia

Rhein, an anthraquinone compound isolated from rhubarb, has been shown to improve glucose metabolism disorders in diabetic mice. The mechanism underlying the protective effect of rhein, however, remains unknown. Here, we demonstrate that rhein can protect the pancreatic β-cells against hyperglycemia...

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Detalhes bibliográficos
Main Authors: Liu, Jing, Chen, Zhaohong, Zhang, Yujing, Zhang, Mingchao, Zhu, Xiaodong, Fan, Yun, Shi, Shaolin, Zen, Ke, Liu, Zhihong
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806614/
https://ncbi.nlm.nih.gov/pubmed/23919963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0251
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