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Genomic Stability: FANCJ-Dependent G4 DNA Repair

G-rich regions have the potential to form G4 DNA upon replication, which can lead to genomic instability. FANCJ, a G4 DNA helicase, has been shown to be critical for the stability of regions that match the G4 signature motif by experiments analyzing its nematode homolog.

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Détails bibliographiques
Auteur principal: Maizels, Nancy
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806494/
https://ncbi.nlm.nih.gov/pubmed/18644339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.06.011
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