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Gene function correlates with potential for G4 DNA formation in the human genome

G-rich genomic regions can form G4 DNA upon transcription or replication. We have quantified the potential for G4 DNA formation (G4P) of the 16 654 genes in the human RefSeq database, and then correlated gene function with G4P. We have found that very low and very high G4P correlates with specific f...

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Autori principali: Eddy, Johanna, Maizels, Nancy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557811/
https://ncbi.nlm.nih.gov/pubmed/16914419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl529
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