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Multiple Aspects of Gene Dysregulation in Huntington’s Disease

Huntington’s Disease (HD) is a genetic neurodegenerative disease caused by a CAG expansion in the gene encoding Huntingtin (Htt). It is characterized by chorea, cognitive, and psychiatric disorders. The most affected brain region is the striatum, and the clinical symptoms are directly correlated to...

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Detalhes bibliográficos
Main Authors: Moumné, Lara, Betuing, Sandrine, Caboche, Jocelyne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806340/
https://ncbi.nlm.nih.gov/pubmed/24167500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2013.00127
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