A Randomized Phase II Trial Comparing 3-hour Versus 96-hour Infusion Schedules of Paclitaxel for the Treatment of Metastatic Breast Cancer

PURPOSE: To compare efficacy and toxicity profiles of paclitaxel using 3-hour versus 96-hour infusion schedules. EXPERIMENTAL DESIGN: Patients with metastatic breast cancer were randomized to receive paclitaxel starting at a dose of 250 mg/m(2) IV over 3 hours every 21 days or paclitaxel starting at...

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Détails bibliographiques
Auteurs principaux: Moulder, Stacy L., Holmes, Frankie A., Tolcher, Anthony W., Thall, Peter, Broglio, Kristine, Valero, Vicente, Buzdar, Aman U., Arbuck, Susan G., Seidman, Andrew, Hortobagyi, Gabriel N.
Format: Artigo
Langue:Inglês
Publié: 2010
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806193/
https://ncbi.nlm.nih.gov/pubmed/20052721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24870
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