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Phase I Study of Paclitaxel by Three‐hour Infusion: Hypotension Just after Infusion Is One of the Major Dose‐limiting Toxicities

The primary objectives of this study were to determine the maximum tolerated dose (MTD) of paclitaxel administered by 3‐h infusion to patients with solid tumors, and to characterize the pharmacokinetics of a 3‐h infusion in comparison with those of a 24‐h infusion. Twenty‐seven patients each receive...

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Detalhes bibliográficos
Publicado no:Jpn J Cancer Res
Main Authors: Tamura, Tomohide, Sasaki, Yasutsuna, Nishiwaki, Yutaka, Saijo, Nagahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5920663/
https://ncbi.nlm.nih.gov/pubmed/8636011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1995.tb03316.x
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