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Peripheral Blood B Cell Subset Skewing Is Associated with Altered Cell Cycling and Intrinsic Resistance to Apoptosis and Reflects a State of Immune Activation in Chronic Hepatitis C Virus Infection

Chronic hepatitis C virus (HCV) infection is associated with B cell activation, although underlying mechanisms are unclear. To investigate B cell regulation during HCV infection, we measured bulk B cell CpG and Staphylococcus aureus Cowan-induced IgG Ab-secreting cell (ASC) frequency, HCV and tetanu...

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Detalhes bibliográficos
Main Authors: Sugalski, Julia M., Rodriguez, Benigno, Moir, Susan, Anthony, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805966/
https://ncbi.nlm.nih.gov/pubmed/20656924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000879
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